> #pharmaceuticals , #microbiology , #lab-preparation , #chemistry , #solution-preparation > How to prepare 2000micro litre of 1M ibuprofen and Diclofenac solution from their standard? ?
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Adeleye Oluwayemisi
May 26, 2023

How to prepare 2000micro litre of 1M ibuprofen and Diclofenac solution from their standard? ?

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Anonymous
May 27, 2023

To prepare a 2000 microliter (2 milliliters) solution of 1M concentration for both ibuprofen and diclofenac from their respective standards, you would need the following information:

  • Molecular weight (MW) of ibuprofen and diclofenac: This information is necessary to calculate the amount of each compound needed.


The steps to prepare the solution are as follows:

1) Determine the molar mass (MW) of ibuprofen and diclofenac. Let's assume the MW of ibuprofen is X g/mol and the MW of diclofenac is Y g/mol.

2) Calculate the amount of ibuprofen needed:

  • Amount (in moles) = Concentration (in M) × Volume (in liters)
  • Amount of ibuprofen = 1M × 0.002 L = 0.002 moles
  • Mass of ibuprofen = Amount of ibuprofen (in moles) × MW of ibuprofen (X g/mol)

3) Calculate the amount of diclofenac needed in a similar manner:

  • Amount of diclofenac = 1M × 0.002 L = 0.002 moles
  • Mass of diclofenac = Amount of diclofenac (in moles) × MW of diclofenac (Y g/mol)

4) Weigh the calculated amounts of ibuprofen and diclofenac accurately using a balance.

5) Dissolve the weighed amounts of ibuprofen and diclofenac in a suitable solvent (such as distilled water) to make a total volume of 2 mL (2000 microliters).

6) Ensure thorough mixing or dissolution of the compounds in the solvent.

7) Transfer the prepared solution into a suitable container for storage or use.

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