> #biology , #cell-biology > It is expected that as a cell becomes larger in size, it would normally lose its metabolic efficiency. Explain the concept underlying this fact.
Anonymous
more than 4 weeks ago

It is expected that as a cell becomes larger in size, it would normally lose its metabolic efficiency. Explain the concept underlying this fact.

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ChatGPT
more than 4 weeks ago
As a cell becomes larger in size, its volume increases at a faster rate than its surface area. This means that the cell's surface area to volume ratio decreases as it grows larger.

The surface area of a cell is important for the exchange of nutrients, gases, and waste products with its environment. A larger surface area allows for more efficient exchange of these substances.

On the other hand, the volume of a cell is related to its metabolic activity. As a cell grows larger, its volume increases and more metabolic processes need to occur to support the cell's functions. However, the surface area available for nutrient exchange does not increase at the same rate, leading to a decrease in the cell's metabolic efficiency.

This decrease in metabolic efficiency can result in slower nutrient uptake, slower waste removal, and overall decreased cellular function. This is why larger cells are often less efficient metabolically compared to smaller cells.
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Google Gemini AI
more than 4 weeks ago
As a cell becomes larger in size, it experiences a decrease in metabolic efficiency due to the increasing surface area to volume ratio.

Surface Area to Volume Ratio:

- The surface of the cell, which facilitates vital processes like nutrient uptake and waste excretion, increases in proportion to the square of the cell's radius (Surface area = 4πr²).
- The volume of the cell, which contains the cell's machinery and organelles, increases in proportion to the cube of the cell's radius (Volume = 4/3πr³).
- As the cell grows larger, the surface area-to-volume ratio decreases, meaning that the cell has a relatively smaller surface area for exchange of materials with its surroundings compared to its internal volume.

Metabolic Efficiency Decline:

This reduced surface area-to-volume ratio affects metabolic efficiency as follows:

- Nutrient Uptake: A smaller surface area limits the cell's ability to take in essential nutrients from the environment, such as oxygen and glucose.
- Waste Excretion: The reduced surface area hinders the removal of metabolic waste products, leading to their accumulation within the cell.
- Diffusion Limitation: As the cell grows larger, the diffusion distance for nutrients and waste to reach the inner regions of the cell increases, slowing down these processes.
- Oxygen Supply: The diffusion of oxygen from the surface of the cell to its interior is limited by the surface area-to-volume ratio. Larger cells may experience oxygen deprivation in the inner regions, impairing cellular respiration and metabolic efficiency.

Consequences of Low Metabolic Efficiency:

Low metabolic efficiency can lead to:

- Impaired cell function and growth
- Reduced ability to respond to environmental demands
- Increased susceptibility to oxidative stress
- Reduced ability to divide and proliferate

Therefore, as a cell becomes larger in size, its surface area-to-volume ratio decreases, leading to a decline in metabolic efficiency and potentially compromising cellular function and viability.
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