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Describe multiplication of plasmodium in red blood cells????
edson sospeter
Jan 29
Describe multiplication of plasmodium in red blood cells????
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Jan 29
Multiplication of Plasmodium in red blood cells is a crucial step in the life cycle of the parasite and is responsible for the symptoms of malaria. Plasmodium is a protozoan parasite that causes malaria in humans.
The process begins when an infected female Anopheles mosquito bites a human and injects sporozoites, the infective stage of the parasite, into the bloodstream. These sporozoites travel to the liver, where they invade liver cells and multiply asexually, forming thousands of merozoites.
After a few days, the merozoites are released into the bloodstream and invade red blood cells. Inside the red blood cells, the merozoites undergo further multiplication through a process called schizogony or erythrocytic schizogony. During this process, the merozoite replicates its genetic material and divides multiple times, forming a multinucleated structure called a schizont.
The schizont then undergoes a process of cytokinesis, where it divides into multiple daughter cells called merozoites. These merozoites are released from the infected red blood cell, which ruptures, leading to the characteristic cyclic fevers associated with malaria.
The released merozoites can then invade new red blood cells and repeat the multiplication process, leading to a rapid increase in parasite numbers within the bloodstream. This multiplication cycle occurs every 48 to 72 hours, depending on the species of Plasmodium.
The multiplication of Plasmodium in red blood cells leads to the destruction of these cells, causing anemia and other symptoms associated with malaria, such as fever, chills, fatigue, and organ damage. It is also during this stage that the parasite can undergo sexual reproduction, forming male and female gametocytes, which can be taken up by mosquitoes during a blood meal, completing the life cycle of the parasite.
The process begins when an infected female Anopheles mosquito bites a human and injects sporozoites, the infective stage of the parasite, into the bloodstream. These sporozoites travel to the liver, where they invade liver cells and multiply asexually, forming thousands of merozoites.
After a few days, the merozoites are released into the bloodstream and invade red blood cells. Inside the red blood cells, the merozoites undergo further multiplication through a process called schizogony or erythrocytic schizogony. During this process, the merozoite replicates its genetic material and divides multiple times, forming a multinucleated structure called a schizont.
The schizont then undergoes a process of cytokinesis, where it divides into multiple daughter cells called merozoites. These merozoites are released from the infected red blood cell, which ruptures, leading to the characteristic cyclic fevers associated with malaria.
The released merozoites can then invade new red blood cells and repeat the multiplication process, leading to a rapid increase in parasite numbers within the bloodstream. This multiplication cycle occurs every 48 to 72 hours, depending on the species of Plasmodium.
The multiplication of Plasmodium in red blood cells leads to the destruction of these cells, causing anemia and other symptoms associated with malaria, such as fever, chills, fatigue, and organ damage. It is also during this stage that the parasite can undergo sexual reproduction, forming male and female gametocytes, which can be taken up by mosquitoes during a blood meal, completing the life cycle of the parasite.
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