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Ex- Vivo gene therapy?
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Dec 11, 2023
Ex-vivo gene therapy is a type of gene therapy that involves the manipulation of genes outside of the body before they are reintroduced into the patient. In this approach, cells are taken from the patient's body and modified in the laboratory to correct a genetic defect or introduce a therapeutic gene. The modified cells are then reinfused back into the patient's body, where they can produce the desired therapeutic effect.
This technique is often used when the target cells are difficult to access directly in the body or when a large number of cells need to be modified. Ex-vivo gene therapy has been used in the treatment of various genetic disorders, such as severe combined immunodeficiency (SCID) and certain types of cancer.
The process of ex-vivo gene therapy typically involves isolating cells from the patient, modifying the cells in the laboratory using techniques like viral vectors or gene editing tools, and then expanding the modified cells in culture. Once a sufficient number of modified cells are obtained, they are infused back into the patient's body, where they can integrate into the target tissues and produce the desired therapeutic effect.
Ex-vivo gene therapy has shown promising results in clinical trials and has the potential to provide long-term or even permanent treatment for genetic diseases. However, it is a complex and expensive procedure that requires specialized facilities and expertise.
This technique is often used when the target cells are difficult to access directly in the body or when a large number of cells need to be modified. Ex-vivo gene therapy has been used in the treatment of various genetic disorders, such as severe combined immunodeficiency (SCID) and certain types of cancer.
The process of ex-vivo gene therapy typically involves isolating cells from the patient, modifying the cells in the laboratory using techniques like viral vectors or gene editing tools, and then expanding the modified cells in culture. Once a sufficient number of modified cells are obtained, they are infused back into the patient's body, where they can integrate into the target tissues and produce the desired therapeutic effect.
Ex-vivo gene therapy has shown promising results in clinical trials and has the potential to provide long-term or even permanent treatment for genetic diseases. However, it is a complex and expensive procedure that requires specialized facilities and expertise.
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