> #biology , #endocrinology > Outline functions of parathyroxine hormone??
edson sospeter
Dec 6, 2023

Outline functions of parathyroxine hormone??

1 view
1 view

1 answer

Sort By
Dec 6, 2023
1. Regulation of calcium levels: Parathyroid hormone (PTH) plays a crucial role in maintaining calcium homeostasis in the body. It increases the levels of calcium in the blood by stimulating the release of calcium from bones, enhancing the absorption of calcium from the intestines, and reducing the excretion of calcium by the kidneys.

2. Bone remodeling: PTH stimulates the activity of osteoclasts, which are responsible for breaking down bone tissue. This process, known as bone resorption, releases calcium into the bloodstream. PTH also inhibits the activity of osteoblasts, which are responsible for bone formation.

3. Kidney function: PTH acts on the kidneys to increase the reabsorption of calcium and decrease the reabsorption of phosphate. This helps to maintain appropriate levels of calcium and phosphate in the blood.

4. Vitamin D activation: PTH stimulates the production of active vitamin D (calcitriol) in the kidneys. Calcitriol enhances the absorption of calcium and phosphate from the intestines, further contributing to the regulation of calcium levels.

5. Regulation of parathyroid gland activity: PTH has a negative feedback loop on the parathyroid glands themselves. When calcium levels in the blood are high, PTH secretion is inhibited, and when calcium levels are low, PTH secretion is stimulated.

6. Regulation of magnesium levels: PTH also plays a role in the regulation of magnesium levels in the blood. It increases the excretion of magnesium by the kidneys, helping to maintain appropriate levels of this mineral.

Overall, the functions of parathyroid hormone are centered around maintaining calcium homeostasis in the body, primarily by increasing calcium levels in the blood through bone resorption, enhancing intestinal absorption, and reducing renal excretion.

Similar Questions


© 2024 - Quanswer