> #biology , #medical > Explain why a person of blood group B cannot receive blood from a blood group A donor? ?
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GRACE AKELLO
more than 2 weeks ago

Explain why a person of blood group B cannot receive blood from a blood group A donor? ?

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ChatGPT
more than 2 weeks ago
A person of blood group B cannot receive blood from a blood group A donor because they have different antigens on their red blood cells. Blood group A individuals have A antigens on their red blood cells, while blood group B individuals have B antigens.

If a person with blood group B receives blood from a donor with blood group A, their immune system will recognize the A antigens as foreign and attack the transfused red blood cells. This can lead to a severe immune response, known as a transfusion reaction, which can be life-threatening.

Therefore, it is important to match blood types carefully to ensure compatibility and prevent adverse reactions during blood transfusions.
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Google Gemini AI
more than 2 weeks ago
A person of blood group B cannot receive blood from a blood group A donor because:

1. Blood Cell Surface Markers:
Red blood cells have surface markers called antigens. Blood group A cells have the A antigen on their surface, while blood group B cells have the B antigen.

2. Antibodies in the Plasma:
Plasma contains antibodies that are specific to foreign antigens. Blood group B individuals have anti-A antibodies in their plasma, which recognize and bind to the A antigen.

3. Transfusion Reaction:
If blood group B is transfused with blood group A, the anti-A antibodies in the recipient's plasma will bind to the A antigens on the transfused red blood cells. This binding triggers a series of immune reactions, including:

- Complement activation: Antibodies activate the complement system, which leads to the destruction of the transfused red blood cells.
- Hemolysis: The complement system causes the red blood cells to rupture, releasing hemoglobin.
- Anaphylaxis: In severe cases, the transfusion reaction can lead to anaphylaxis, a life-threatening allergic reaction.

To prevent these harmful reactions, only blood from compatible blood groups is transfused. In this case, a person of blood group B can only receive blood from blood group B or O (universal donor), which do not contain the A antigen that triggers the immune response.
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