State the 5 differential diagnoses for gonorrhea,identify 5 investigations done to confirm gonorrhea,give treatment of gonorrhea?

Differential diagnoses for gonorrhea:
1. Chlamydia
2. Urinary tract infection
3. Pelvic inflammatory disease
4. Genital herpes
5. Non-gonococcal urethritis

Investigations to confirm gonorrhea:
1. Nucleic acid amplification tests (NAATs)
2. Gram stain of urethral or cervical discharge
3. Culture of the organism
4. Polymerase chain reaction (PCR) testing
5. Blood tests for antibodies to the bacteria

Treatment of gonorrhea:
The recommended treatment for gonorrhea is a combination of antibiotics, typically ceftriaxone and azithromycin. It is important to complete the full course of antibiotics as prescribed by a healthcare provider to ensure the infection is fully treated. It is also important to inform any sexual partners so they can be tested and treated if necessary.

Differential Diagnoses for Gonorrhea

1. Chlamydia
2. Genital Herpes
3. Trichomoniasis
4. Bacterial Vaginosis
5. Pelvic Inflammatory Disease (PID)

Investigations to Confirm Gonorrhea

1. Gram stain of urethral or cervical discharge
2. Nucleic Acid Amplification Test (NAAT)
3. Culture of urethral or cervical discharge
4. Serological test for antibodies to Neisseria gonorrhoeae
5. Antigen detection test

Treatment of Gonorrhea

Uncomplicated Gonorrhea

- Injectable
- Ceftriaxone 125 mg IM single dose
- Azithromycin 2 g PO single dose
- Oral
- Cefixime 400 mg PO single dose
- Doxycycline 100 mg PO bid for 7 days

Complicated Gonorrhea

- Injectable
- Ceftriaxone 1 g IM every 24 hours for 3-5 days
- Oral
- Azithromycin 500 mg PO once daily for 3-5 days

Partner Management

- All sexual partners within the last 2 months should be notified, tested, and treated, even if asymptomatic.
- Abstinence is recommended until both partners have been treated and are confirmed to be cured.